CSIR NET Life Sciences Questions with Detailed Solutions, Download PDF

The Council of Scientific and Industrial Research National Eligibility Test (CSIR NET) is one of the most prestigious exams in India for aspiring researchers and academicians. Scheduled to be held from 28 February 2025 to 2 March 2025, this exam serves as a gateway for Junior Research Fellowships (JRF) and eligibility for lectureship in universities and colleges across India. For candidates preparing for the Life Sciences paper, having access to CSIR NET Life Sciences questions with detailed solutions has been provided below.

CSIR NET Life Sciences Questions with Detailed Solutions

Preparing for the CSIR NET Life Sciences exam requires a deep understanding of the subject, along with practice through previous years’ questions and mock tests. Solving CSIR NET Life Sciences questions with detailed solutions helps candidates understand the exam pattern, identify important topics, and improve problem-solving skills. These solutions provide step-by-step explanations, making it easier for aspirants to grasp complex concepts and avoid common mistakes.

CSIR NET Life Sciences: Overview

The CSIR NET Life Sciences exam is a highly competitive test conducted to determine the eligibility of candidates for Junior Research Fellowships (JRF) and lectureship in Indian universities and colleges. Scheduled to be held from 28 February 2025 to 2 March 2025, this exam evaluates candidates’ knowledge, analytical skills, and understanding of Life Sciences. The exam is divided into three parts. The total duration of the exam is 3 hours, and the maximum marks are 200. Below is a detailed overview of the exam pattern and mark distribution in a concise table format:

Download CSIR NET Life Sciences Questions with Detailed Solutions

To aid your preparation, you can download CSIR NET Life Sciences questions with detailed solutions in PDF format. By practicing these questions, you can strengthen your conceptual understanding, improve time management, and boost your confidence for the exam.

CSIR NET Life Sciences Questions

Q1. Which one of the following enzymes does NOT catalyze the oxidation of a substrate by reducing the electron acceptor, NAD⁺?
(a) Lactate dehydrogenase
(b) Pyruvate dehydrogenase
(c) Succinate dehydrogenase
(d) Isocitrate dehydrogenase

Q2. The pH of endocytic vesicles is 5.2, and the pH of gastric juice is 2.0. The endocytic vesicle has a [H+]that is:
(a) 15.85 times lower than that of gastric juice.
(b) 0.1585 times lower than that of gastric juice.
(c) 158.5 times lower than that of gastric juice.
(d) 1585 times lower than that of gastric juice. .

Q3. One strand of a palindromic dsDNA is composed of 5′-CCGCGGCGG-3′. Which one of the following forms of nucleic acid structures will be adopted in water if sense and antisense strands are mixed in equal proportion followed by annealing?
(a) A-form of double-stranded nucleic acid
(b) B-form of double-stranded nucleic acid
(c) Z-form of double-stranded nucleic acid
(d) Both will remain as single strands

Q4. Which one of the following pairs of metabolic intermediates does NOT provide a backbone carbon skeleton for the synthesis of amino acids?
(a) Succinate and citrate
(b) 3-phosphoglycerate and phosphoenolpyruvate
(c) Ribose 5-phosphate and erythrose 4-phosphate
(d) α-ketoglutarate and oxaloacetate

Q5. Fifteen spontaneous Ara⁻ mutants of E. coli, unable to utilize arabinose as a sole carbon source at 42°C but able to utilize it at 30°C, were isolated. Based on the above information, which one of the following options represents the most likely type of the mutations?
(a) Deletions
(b) Inversions
(c) Frameshift mutations
(d) Mis-sense mutations

Q6. Which one of the following statements about the distribution of chromosomes within the interphase nucleus of a mammalian cell is correct?
(a) Chromosomes are randomly distributed within the nuclear volume.
(b) The gene-poor chromosomes tend to locate towards the nuclear envelope.
(c) The larger chromosomes tend to locate at the nuclear periphery.
(d) Centromeric regions of all the chromosomes tend to concentrate at the center of the nucleus.

Q7. Which cell cycle phase is typically the shortest in mammalian cells?
(a) G0 phase
(b) G1 phase
(c) G2 phase
(d) Mitosis

Q8. Porins, which are normally present on the outer mitochondrial membrane, reach their destination by:
(a) Direct synthesis of porins on the mitochondrial membrane by the mitochondrial protein synthesis machinery.
(b) Synthesis on the ER and transport via vesicles to the mitochondria.
(c) Synthesis in the cytosol, import by TOM complex, and insertion from the inter-mitochondrial membrane space.
(d) Synthesis in the cytosol, import by TIM complex, and insertion in the membrane.

Q9. During replication, over-winding of DNA is caused by ____ and removed by ____:
(a) Primase, topoisomerase
(b) Primase, single-stranded binding protein
(c) Helicase, gyrase
(d) Helicase, DNA polymerase

Q10. P-bodies are discrete cytoplasmic collections of RNAs and proteins that are involved in:
(a) Deadenylation, decapping, and mRNA degradation
(b) Deadenylation and mRNA degradation only
(c) Deadenylation and decapping only
(d) Decapping and mRNA degradation only

Solutions

S1. Ans. (c)

S2. Ans. (d)

S3. Ans. (b)

S4. Ans. (a)

S5. Ans. (d)

S6. Ans. (b)

S7. Ans. (d)

S8. Ans.(c)

S9. Ans. (c)

S10. Ans.(a)

Benefits of CSIR NET Life Sciences Questions

• Improved understanding: Detailed explanations enhance your grasp of the subject matter and help you connect different concepts.
• Enhanced problem-solving skills: Working through solutions exposes you to different problem-solving approaches and helps you develop your own strategies.
• Better time management: Practicing with previous year’s papers under timed conditions helps you improve your speed and accuracy.
• Increased confidence: Solving a variety of questions and understanding the solutions boosts your confidence and reduces exam anxiety.

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